🇺🇸 United States Episodes

In just 6 years, Facebook grew to 2 billion users and 14,000 employees. How? Well, first, they hired COO Sheryl Sandberg. And she knew that to lead a fast-changing organization, you have to be as skilled at breaking plans as you are at making them. Great scale leaders know how to pivot, because every day there are new competitors, new threats, new opportunities. Sandberg shares the practical, tactical on-the-ground leadership lessons she learned while scaling at Google and Meta.Read a transcript of this episode: https://mastersofscale.com/sheryl-sandberg-lead-lead-again/Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

My guest today is Martin Casado. Martin is a general partner at Andreessen Horowitz where he focuses on digital infrastructure. Before joining a16z, Martin pioneered software-defined networking and co-founded Nicira, which was bought by VMware for $1.3 billion in 2012. Martin has studied, built, and invested in digital infrastructure his whole career and is the perfect person to discuss the most interesting aspects of the industry. Please enjoy this great conversation with Martin Casado.   For the full show notes, transcript, and links to mentioned content, check out the episode page here.   -----   This episode is brought to you by Tegus. Tegus streamlines the investment research process so you can get up to speed and find answers to critical questions on companies faster and more efficiently. The Tegus platform surfaces the hard-to-get qualitative insights, gives instant access to critical public financial data through BamSEC, and helps you set up customized expert calls. It’s all done on a single, modern SaaS platform that offers 360-degree insight into any public or private company. As a listener, you can take Tegus for a free test drive by visiting tegus.co/patrick. And until 2023 every Tegus license comes with complimentary access to BamSec by Tegus.   -----   Today's episode is brought to you by Brex, the integrated financial platform trusted by the world's most innovative entrepreneurs and fastest-growing companies. With Brex, you can move money fast for instant impact with high-limit corporate cards, payments, venture debt, and spend management software all in one place. Ready to accelerate your business? Learn more at brex.com/best.   -----   Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.    Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.   Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.   Follow us on Twitter: @patrick_oshag | @JoinColossus   Show Notes [00:02:43] - [First question] - The state of the digital infrastructure industry today  [00:04:02] - The major stages and eras of cloud technology  [00:06:30] - Overview of Dropbox’s story and the two major trends at the time of its emergence [00:10:12] - Lost margin and lost market cap from big users of the public cloud  [00:12:14] - Whether or not there is a headwind coming for public cloud providers [00:17:33] - How entrepreneurs might go after the biggest public cloud providers [00:19:37] - His view on API first companies and granular monetizable units in growing markets [00:23:20] - Developer facing tools and what works well when going to market  [00:27:12] - The difference between a front-end and back-end developer and what is changing in their responsibilities  [00:28:45] - What he looks for as an investor when he’s processing a new API first company [00:30:31] - Common redflags and disqualifying observations for an API first company  [00:36:35] - Frank Slootman Episode; Snowflake’s offering for their users, their explosive growth, and primitives in their sector [00:39:06] - The history of digital security and potential opportunities as an investor [00:40:19] - How digital infrastructure intersects with the real world and hardware world [00:43:33] - How to screen out people for their potential to deliver transformative technology [00:47:45] - Things he’s most intrigued about by cryptocurrencies as an infrastructure person [00:52:49] - The kindest thing anyone has ever done for him

Growing up in the public eye, multi-hyphenate creator Bryce Dallas Howard experienced the familiar pressure to share her life with the world on social media. But with her mother’s steadfast guidance, Howard learned to set personal boundaries and savor the beauty of private moments. In this personal talk, she draws on three generations of family wisdom to remind us that “a private life makes a public life worth living.”For a chance to give your own TED Talk, fill out the Idea Search Application: ted.com/ideasearch.Interested in learning more about upcoming TED events? Follow these links:TEDNext: ted.com/futureyouTEDSports: ted.com/sportsTEDAI Vienna: ted.com/ai-viennaTEDAI San Francisco: ted.com/ai-sf Hosted on Acast. See acast.com/privacy for more information.

My guest this episode is Dr. Paul Conti, M.D., a psychiatrist and expert in treating trauma, personality disorders and psychiatric illnesses and challenges of various kinds. Dr. Conti earned his MD at Stanford and did his residency at Harvard Medical School. He now runs the Pacific Premiere Group—a clinical practice helping people heal and grow from trauma and other life challenges. We discuss trauma: what it is and its far-reaching effects on the mind and body, as well as the best treatment approaches for trauma. We also explore how to choose a therapist and how to get the most out of therapy, as well as how to do self-directed therapy. We discuss the positive and negative effects of antidepressants, ADHD medications, alcohol, cannabis, and the therapeutic potential of psychedelics (e.g., psilocybin and LSD), ketamine and MDMA. This episode is must listen for anyone seeking or already doing therapy, processing trauma, and/or considering psychoactive medication. Both patients and practitioners ought to benefit from the information. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps (00:00:00) Dr. Paul Conti, Trauma & Recovery  (00:02:48) Sponsors: AG1, LMNT (00:07:00) Defining Trauma  (00:14:05) Guilt & Shame, Origins of Negative Emotions (00:21:38) Repeating Trauma, the Repetition Compulsion  (00:28:23) How to Deal with Trauma & Negative Emotions/Arousal  (00:37:17) Processing Trauma, Do You Always Need a Therapist? (00:45:30) Internal Self-talk, Punishing Narratives & Negative Fantasies  (00:51:10) Short-Term Coping Mechanisms vs. Long-Term Change (00:53:22) Tools: Processing Trauma on Your Own, Journaling  (00:57:00) Sublimination of Traumatic Experiences  (01:02:34) Tool: Finding a Good Therapist  (01:07:20) Optimizing the Therapy Process, Frequency, Intensity   (01:14:51) Tool: Self-Awareness of Therapy Needs, Mismatch of Needs (01:16:35) Self-talk & Journaling, Talking to Trusted Individuals  (01:19:00) Prescription Drugs & Treating Trauma, Antidepressants, Treating Core Issues   (01:28:35) Short-term vs. Long-Term Use of Prescription Drugs, Antidepressants (01:32:18) Attention Deficient Hyperactivity Disorder (ADHD) & Prescription Drugs  (01:37:31) Negative Effects of ADHD Prescription Drugs  (01:40:37) Alcohol, Cannabis – Positive & Negative Effects (01:44:53) Psychedelics: Psylocibin & LSD, Therapeutic Uses, Trauma Recovery     (01:54:32) Sentience, Language, Animals   (01:55:48) Psychedelic Hallucinations, Trauma Recovery  (02:00:01) MDMA (Therapeutic Uses) (02:04:47) Clinical Aspects of MDMA (02:07:28) Language, Processing Trauma, Social Media, Societal Divisions  (02:15:09) Defining “Taking Care of Oneself” (02:21:13) Dr. Conti, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices

Our Surprise Guest(s) this week are the dynamic duo: Phil Lord and Christopher Miller. “The Hall & Oates of film & television” make us a few table-side Caesar salads and tell us their true Hollywood stories. After all, the ladies love a coupl’a cartoonists doodling away in the studio.

Dr Joanna Williams is the Founder of Cieo, associate editor of Spiked and an author. The last few years has seen progressive ideas capture institutions, academics and headlines. But how much has this ideology actually trickled down to making a real impact in the world? Is it just a moral panic about a moral panic or is there something to really be concerned about? Expect to learn why police officers are being told to actively refer to themselves as woke, how 3 month old babies can be racist, why air conditioning is a tool of the patriarchy, whether the people pushing these narratives actually believe this stuff, what the future of progressive messaging has in store and much more... Sponsors: Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/ Get 15% discount on Craftd London’s jewellery at https://bit.ly/cdwisdom (use code MW15) Get 2 weeks free access to Wondrium by going to https://www.wondrium.com/modernwisdom (discount automatically applied) Get a Free Sample Pack of all LMNT Flavours at https://www.drinklmnt.com/modernwisdom (discount automatically applied) Extra Stuff: Buy How Woke Won - https://amzn.to/38YNu1h Follow Joanna on Twitter - https://twitter.com/jowilliams293  To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact/  Learn more about your ad choices. Visit megaphone.fm/adchoices

We sit down with a16z General Partner Katherine Boyle to discuss investing in “American Dynamism”, why it’s so important and why now is the right time to pursue it. Katherine has a fascinating background, beginning her career as a reporter at The Washington Post before entering the VC world first at Founders Fund, then General Catalyst and now a16z. Her perspectives don’t fit neatly in any box — political, economic or otherwise — and we have a great conversation exploring them. Tune in!This episode has video! You can watch it on YouTube.Sponsors:WorkOS: https://bit.ly/workos25Sierra: https://bit.ly/acquiredsierraSentry: https://bit.ly/acquiredsentryAnthropic: https://bit.ly/acquiredclaude25More Acquired!Get email updates with hints on next episode and follow-ups from recent episodesJoin the SlackSubscribe to ACQ2Merch Store!© Copyright 2015-2025 ACQ, LLCLinks:Katherine’s post on Building American DynamismMarc Andreessen’s It’s Time to BuildKatherine’s Substack‍Note: Acquired hosts and guests may hold assets discussed in this episode. This podcast is not investment advice, and is intended for informational and entertainment purposes only. You should do your own research and make your own independent decisions when considering any financial transactions.

How does the profitability of family firms stack up against the rest? Has nepotism become more taboo over time? And why are 90 percent of adoptees in Japan not children but adults?

Jonathan Haidt is a social psychologist at NYU and author of The Coddling of the American Mind, The Righteous Mind, and The Happiness Hypothesis. Please support this podcast by checking out our sponsors: – Uncruise: https://uncruise.com/pages/lex – Notion: https://notion.com/startups to get up to $1000 off team plan – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium – Magic Spoon: https://magicspoon.com/lex and use code LEX to get $5 off – Eight Sleep: https://www.eightsleep.com/lex and use code LEX to get special savings EPISODE LINKS: Jonathan’s Twitter: https://twitter.com/JonHaidt Jonathan’s Website: https://jonathanhaidt.com Documents & Articles: 1. Social Media and Political Dysfunction: A Collaborative Review: https://docs.google.com/document/d/1vVAtMCQnz8WVxtSNQev_e1cGmY9rnY96ecYuAj6C548/edit 2. Teen Mental Health Testimony: https://www.judiciary.senate.gov/imo/media/doc/Haidt%20Testimony.pdf 3. The Atlantic article: https://www.theatlantic.com/magazine/archive/2022/05/social-media-democracy-trust-babel/629369/ Books: 1. The Coddling of the American Mind (book): https://amzn.to/3MW4HqL 2. The Righteous Mind (book): https://amzn.to/3to0tkj 3. The Happiness Hypothesis (book): https://amzn.to/3Mb1xP2 PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:57) – Social media and mental health (21:45) – Mark Zuckerberg (31:23) – Children’s use of social media (42:08) – Social media and democracy (58:14) – Elon Musk and Twitter (1:14:45) – Anonymity on social media (1:20:44) – Misinformation (1:27:38) – Social media benefits (1:30:22) – Political division on social media (1:36:54) – Future of social media (1:42:46) – Advice for young people

Tyler Cowen is the Holbert L. Harris Chair of Economics at George Mason University, a columnist, podcaster and an author. Finding and recruiting the best talent is perhaps the most important job that an organisation has. Skilful, enthusiastic, keen staff can make or break a business, so why is it that most companies are mostly useless when it comes to discovering talent? Expect to learn whether population collapse is coming very soon, whether talent is innate or developed, why there is a crisis of talent when we have more people on earth than ever before, whether you should look at someone's parents before hiring them, the best questions to ask in an interview, what SpaceX's hiring strategy teaches us about thoroughness, how Tyler screens young staff for the most original thinkers and much more... Sponsors: Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/ Get 83% discount & 3 months free from Surfshark VPN at https://surfshark.deals/MODERNWISDOM (use code MODERNWISDOM) Get 15% discount on Upgraded Formulas Test Kit at https://upgradedformulas.com/ (use code: MW15) Get 20% discount on the highest quality CBD Products from Pure Sport at https://bit.ly/cbdwisdom (use code: MW20) Extra Stuff: Buy Talent - https://amzn.to/3t5cs5Z Follow Tyler on Twitter - https://twitter.com/tylercowen Check out Tyler's website - https://marginalrevolution.com/  To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact/  Learn more about your ad choices. Visit megaphone.fm/adchoices

Life is a constant state of both joy and sorrow, dark and light, bitter and sweet. In a meditative conversation, author Susan Cain explores how being attuned to the bittersweetness of life -- and being fully present for both the happy times and the sad times -- helps us navigate love and loss and connect to the "insane beauty" of the world. (This conversation, hosted by TED current affairs curator Whitney Pennington Rodgers, was part of an exclusive TED Membership event. Visit ted.com/membership to become a TED Member.)Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

When the beloved Simpsons family made its TV debut in 1989, it squarely represented middle-class America. Today ... not so much. That house, those two cars, those three kids all on one salary doesn't seem so believable anymore. Today we examine the changing reality of what middle-class means in America through the Simpsons. It's a wild, musical journey into the heart of the US economy. | Subscribe to our weekly newsletter here.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

In the multitude of metaverses that exist there are infinite possibilities for inclusivity and creativity. Inviting us to craft our own digital universes, Minecraft's game director Agnes Larsson shares how the experience of building and sharing metaverses can foster dialogue, friendship and trust -- pointing to the meaningful impact virtual worlds can have on the real world.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

This talk was recorded LIVE at the All-In Summit in Miami and included slides. To watch on YouTube, check out our All-In Summit playlist: https://bit.ly/aisytplaylist 0:00 Yung Spielburg intros the Besties + Besties give reactions to the All-In Summit 5:56 Miami Mayor Francis Suarez joins the Besties on stage to chat: Miami's emergence as a tech hub, his governing principles, crypto, what the future holds & more Follow Mayor Suarez: https://twitter.com/FrancisSuarez Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect

Joe is joined by Aljamain Sterling, UFC Bantamweight Champion and host of the "Weekly Scraps" podcast. http://www.aljamainsterling.com/ Learn more about your ad choices. Visit podcastchoices.com/adchoices

How do you navigate life's growing number of transitions with meaning, purpose and skill? Writer Bruce Feiler offers a powerful way to handle uncertain, painful and confusing times -- or "lifequakes", as he calls them. Learn how to equip yourself with the essential tools and mindset to ride out (and rewrite) the toughest chapters of your life story, and turn unease and upheaval into growth and renewal.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

This talk was recorded LIVE at the All-In Summit in Miami and included slides. To watch on YouTube, check out our All-In Summit playlist: https://bit.ly/aisytplaylist 0:00 Joe Lonsdale speaks about the problem with higher education and the importance of debate/truth-seeking 10:13 Bestie Q&A with Joe: Why Americans feel victimized, what happened in 1971, getting off the gold standard, school choice, starting UATX Follow Joe: https://twitter.com/JTLonsdale Follow the besties: https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg Intro Video Credit: https://twitter.com/TheZachEffect

"Corporations can be a force for good – and they can also be very successful," says Ken Chenault, chair of investment firm General Catalyst and former longtime CEO of American Express. During the past year, Ken has been an outspoken advocate for business leaders to actively engage in societal matters. After George Floyd’s death, he and Merck CEO Ken Frazier launched OneTen, a coalition to create 1 million jobs for Black Americans that now includes major brands from IBM to Nike to Walmart. Chenault has pushed corporate chiefs to use their leverage to protect voting rights, and he's come out with a platform for Responsible Innovation that puts what he calls “social due diligence” alongside financial due diligence. Standing up for what's right, Ken says, fuels long-term success: "The most important thing is the quest for truth, character, and values."Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

In this special “innovation overview” episode from April 2021, the a16z crypto team and other experts give a primer on crypto and web3, starting from the basics of crypto and how it works to more recent innovations and beyond -- all through the lens of an oral essay.

Tim Kennedy is a Green Beret, Special Forces Sniper, Army Ranger and Professional MMA Fighter. Tim has spent most of his life fighting. Whether that's been against kids in kindergarten, Special Forces selection officers, UFC champions, enemy combatants, ISIS, or his own compulsion to make a mess of his life. He's seen his fair share of pain and discovered a lot of insights through it. Expect to learn whether Tim has ever used BJJ in a combat situation, what motivates him to put himself through the discomfort he's endured, why he refused pain killers throughout his entire MMA career, why he swam a mile out to sea after getting two women pregnant and thinking he had AIDS and much more... Extra Stuff: Buy Scars & Stripes - https://amzn.to/3z1bons Follow Tim on Instagram - https://www.instagram.com/timkennedymma/  Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact/  Learn more about your ad choices. Visit megaphone.fm/adchoices