🇺🇸 United States Episodes

Lee Cronin is a chemist at the University of Glasgow. Please support this podcast by checking out our sponsors: – Paperspace: https://gradient.run/lex to get $15 credit – Athletic Greens: https://athleticgreens.com/lex and use code LEX to get 1 month of fish oil – Notion: https://notion.com/startups to get up to $1000 off team plan – Blinkist: https://blinkist.com/lex and use code LEX to get 25% off premium – Onnit: https://lexfridman.com/onnit to get up to 10% off EPISODE LINKS: Lee’s Twitter: https://twitter.com/leecronin Lee’s Website: https://www.chem.gla.ac.uk/cronin/ Chemify’s Website: https://chemify.io PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (08:31) – Life and chemistry (21:56) – Self-replicating molecules (32:19) – Origin of life (48:45) – Life on Mars (53:49) – Aliens (1:00:30) – Origin of life continued (1:07:24) – Fermi Paradox (1:17:04) – UFOs (1:25:25) – Science and authority (1:31:28) – Pickle experiment (1:34:23) – Assembly theory (2:17:22) – Free will (2:28:37) – Cellular automata (2:52:08) – Chemputation (3:09:23) – Universal programming language for chemistry (3:22:34) – Chemputer safety (3:35:15) – Automated engineering of nanomaterials (3:44:15) – Consciousness (3:53:48) – Joscha Bach (4:05:04) – Meaning of life

Throughout US history, the stories of influential Black mothers have been purposefully obscured -- at a high cost to us all. Sociologist Anna Malaika Tubbs unmasks the lies and designs behind this strategic erasure and highlights the scientific, cultural and historical contributions of Black mothers. Listen in as she details how we can change the narrative to move forward. (This conversation, hosted by TED current affairs curator Whitney Pennington Rodgers, was part of an exclusive TED Membership event. Visit ted.com/membership to become a TED Member.)Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Sam Parr (@TheSamParr) and Shaan Puri (@ShaanVP) are joined by Steph Smith (@StephSmithIO) to discuss why you shouldn't think beyond step 1 when starting a business, how to identify 10X productivity employees, and how to automatically generate side-hustle ideas. ----- Links: * Steph's website - http://stephsmith.io/ * Steph's podcast - http://listenandlearn.co/ * Spring loading community - https://discord.gg/xhhFEwgWTf * NYT First Said - https://twitter.com/NYT_first_said * Nuuly - https://www.nuuly.com/ * MSCHF - https://mschf.xyz/ * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter. ----- Show Notes: (01:30) - Chewie.com Billionaire (6:30) - Are you buying the dip (16:15) - New York Times first said (22:00) - MSCHF (27:00) - Is 10X talent real? (32:30) - Why Steph still works for an employer (40:00) - Nuuly (49:00) - The side hustle generator (01:15:00) - Why Steph still calls her fiancee her "partner" ----- Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more. ----- Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

Tjada D'Oyen McKenna, the CEO of Mercy Corps, an NGO on the front lines of the Ukrainian crisis, provides an inside look on how they’re helping address the needs of refugees. Mercy Corps began scenario planning well in advance of Russia’s aggression, and they’re now deploying food, cash, and social services to those in need. She also cautions about potential negative impacts elsewhere, as troubles in Ukraine pull resources from other struggling populations.Learn more about Mercy Corps: https://www.mercycorps.orgRead a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

With Web3 gathering more momentum than ever before across the tech ecosystem, what can we learn from the recent past of tech adoption? In this episode from December 2018, author and podcaster Brian McCullough talks with a16z general partner Chris Dixon about the origins of the internet, based on Brian’s book, How the Internet Happened: From Netscape to the iPhone.

Matt Rudd is Deputy Editor at The Sunday Times Magazine and an author. Men between the ages of 45 and 49 are at the highest risk of attempting to take their own life. In a world filled with accusations of patriarchal overreach, it seems odd that men are suffering so much with their mental health. It's not good for them, or their wives, or their children. Matt researched men of all ages to work out why men are unhappy and what we can do about it. Expect to learn why your 40's might be the weirdest period of your life, why men would rather be a workaholic than face their internal fears, the challenges with the male denial of mental health problems, why men feel indulgent shame if they're sad, why boys are trained to be competitive in school, how to tell if you're genuinely getting old and much more... Sponsors: Join the Modern Wisdom Community to connect with me & other listeners - https://modernwisdom.locals.com/ Get 20% discount & free shipping on your Lawnmower 4.0 at https://www.manscaped.com/ (use code MODERNWISDOM) Get 20% discount on everything from Lucy at https://uk.lucy.co/ (UK) or https://lucy.co/ (US) (use code: MW20) Get 15% discount on the amazing 6 Minute Diary at https://bit.ly/diarywisdom (use code MW15) Extra Stuff: Buy Man Down - https://amzn.to/3IUKekr Follow Matt on Twitter - https://mobile.twitter.com/mattrudd  Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/modernwisdompodcast Email: https://chriswillx.com/contact/  Learn more about your ad choices. Visit megaphone.fm/adchoices

After World War II devastated the global economy, there was a push for a new universal currency. This is the story of how the U.S. dollar won. | Subscribe to our weekly newsletter here.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Nims is the multi world record breaking mountaineer who climbed all 14 of the world’s ‘Death Zone’ peaks over 8,000m in just 6 months and 6 days. He was part of the first winter ascent of the ‘Savage Mountain’ K2. His film, "14 Peaks: Nothing Is Impossible," is out now on Netflix, as is his best-selling book, "Beyond Possible." Nims is a UNEP Mountain Advocate and founder of the Nimsdai Foundation. Learn more about your ad choices. Visit podcastchoices.com/adchoices

"We have the right to demand budgets to be equitable, to be fair," says economist Maja Bosnic. One way to get there is to make them gender-responsive. With examples from the nearly 80 countries around the world already factoring gender into public finance decisions, she shares how budgets that actively account for gender don't just lead to equality -- they're also more efficient and effective.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) discuss why Time Out is a surprising business that could be worth a billion dollars, whether it's worth buying Russian stocks, and what Shaan would do to build a large right-wing media property. ----- Links: * Time Out - https://www.timeout.com/ * DC Enquirer - https://dcenquirer.com/ * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter. ----- Show Notes: (01:30) - Time Out (8:25) - Russian stocks (11:30) - Right wing media sites ----- Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more. ----- Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

Original Air Date: June 26, 2019 In a live appearance at UCLA’s Royce Hall, Deepak Chopra explains why a belief is simply a "thought that is true for you." He says the world that we create for ourselves is based on these thoughts, and thus beliefs shape our reality. Deepak goes on to discuss how, as babies, we are filled with curiosity, wonder and bliss. But when we start to be conditioned by the world around us, we begin to build a separate self—one that can fill us with anxiety, pressure and fear. Deepak shares why this “separate self” is not who we really are. He also discusses what it's like to become present and aware through meditation, and why this awareness is important to our well-being.

Comedian and writer Tom Papa is the host of the popular podcast "Breaking Bread with Tom Papa", and the co-host, along with Fortune Feimster, of the Netflix radio program "What a Joke with Papa and Fortune." It can be heard daily on Sirius XM. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) share some "drunk business ideas." Ideas that sound ridiculous... but might actually work. ----- * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter. ----- Show Notes: (02:25) - Very long distance girlfriend (10:00) - Extremely large beds (17:10) - HOA Court (25:30) - Business Olympics ----- Past guests on My First Million include Rob Dyrdek, Hasan Minhaj, Balaji Srinivasan, Jake Paul, Dr. Andrew Huberman, Gary Vee, Lance Armstrong, Sophia Amoruso, Ariel Helwani, Ramit Sethi, Stanley Druckenmiller, Peter Diamandis, Dharmesh Shah, Brian Halligan, Marc Lore, Jason Calacanis, Andrew Wilkinson, Julian Shapiro, Kat Cole, Codie Sanchez, Nader Al-Naji, Steph Smith, Trung Phan, Nick Huber, Anthony Pompliano, Ben Askren, Ramon Van Meer, Brianne Kimmel, Andrew Gazdecki, Scott Belsky, Moiz Ali, Dan Held, Elaine Zelby, Michael Saylor, Ryan Begelman, Jack Butcher, Reed Duchscher, Tai Lopez, Harley Finkelstein, Alexa von Tobel, Noah Kagan, Nick Bare, Greg Isenberg, James Altucher, Randy Hetrick and more. ----- Additional episodes you might enjoy: • #224 Rob Dyrdek - How Tracking Every Second of His Life Took Rob Drydek from 0 to $405M in Exits • #209 Gary Vaynerchuk - Why NFTS Are the Future • #178 Balaji Srinivasan - Balaji on How to Fix the Media, Cloud Cities & Crypto #169 - How One Man Started 5, Billion Dollar Companies, Dan Gilbert's Empire, & Talking With Warren Buffett • ​​​​#218 - Why You Should Take a Think Week Like Bill Gates • Dave Portnoy vs The World, Extreme Body Monitoring, The Future of Apparel Retail, "How Much is Anthony Pompliano Worth?", and More • How Mr Beast Got 100M Views in Less Than 4 Days, The $25M Chrome Extension, and More

Women and girls are conditioned to believe success is "a seat at the table." Creator, actress and author Lilly Singh thinks we need to build a better table. In this hilarious, incisive talk, Singh traces the arc of her career from up-and-coming YouTuber to history-making late-night talk show host, offering four ways to build a more inclusive society where girls are encouraged and empowered to do great things.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Megan Gerhardt, management professor at Miami University, studies the impact of generational conflict on organizations. She says too many leaders see generational lines as a source of division that hurts productivity. But her research shows that age is often an untapped source of diversity. When age-diverse teams are managed well, members share more knowledge, skills, and networks with each other. To foster intergenerational collaboration, she lays out a four-part framework that starts with questioning assumptions and ends with embracing mutual learning. Gerhardt is a coauthor of the HBR article "Harnessing the Power of Age Diversity.”

For some entrepreneurs, risk is just part of the game. But for the reluctant entrepreneur, whose endeavors come as a response to a need they've identified, risk can feel more like a necessary evil. That’s why you need to learn to harness risk. Stacey Abrams, an entrepreneur and scale leader both in and outside of politics, is a perfect example of how harnessing risk can be key to your success. Outside of politics, she’s started three companies with her business partner, Lara Hodgson. Their new book, Level Up: Rise Above the Hidden Forces Holding Your Business Back, dives into the lessons learned from those experiences. She also founded and scaled two voting rights organizations: the New Georgia Project and Fair Fight Action, as well as the census mobilization effort Fair Count and the Southern Economic Advancement Project.Read Level Up: Rise Above the Hidden Forces Holding Your Business Back, by Stacey Abrams and Lara HodgsonRead a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

My guest today is Garry Tan, founder and managing partner of early-stage venture firm, Initialized Capital. Before starting Initialized, Garry was a partner at Y Combinator, employee number 10 at Palantir, and co-founder of YC backed blog platform Posterous. Our discussion covers what’s missing in the investment world, how to best systematize venture investments, and what he learned from Paul Graham. Please enjoy my conversation with Garry Tan.   For the full show notes, transcript, and links to mentioned content, check out the episode page here.   -----   This episode is brought to you by Tegus. Tegus is the new digital hub for market intelligence. The Tegus platform empowers Investors and Corporate Development teams to invest smarter by pairing best-in-class technology with the highest quality user-generated content and data. Find out why a majority of the top firms are using Tegus on a daily basis. Head to tegus.co/patrick for your free trial.   -----   This episode is brought to you by Lemon.io. The team at Lemon.io has built a network of Eastern European developers ready to pair with fast-growing startups. We have faced challenges hiring engineering talent for various projects - and Lemon.io offered developers for one-off projects, developers for full start to finish product development, or developers that could be add-ons to the existing team. Check out lemon.io/patrick to learn more.   -----   Invest Like the Best is a property of Colossus, LLC. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.    Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.   Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.   Follow us on Twitter: @patrick_oshag | @JoinColossus   Show Notes [00:02:45] - [First question] - Why he’s interested by software and the global brain [00:06:23] - How the shift from global to local manifests in his investing and company activities [00:11:42] - Ways to increase throughput that would benefit everybody in the investing world  [00:17:13] - What software he would build if there were no limitations and what happens at the systems level of securing deals at Initialize  [00:23:33] - Why there is no objective application process for early-stage capital and how much human judgment we can remove from approving funding [00:26:49] - Shared characteristics amongst new inventions he finds favorable  [00:31:49] - Whether he’s able to evaluate an idea without a prototype [00:33:33] - Why travel planning software was the worst idea of 2012 and what he sees as the bad idea of today [00:36:06] - The most common reasons for failure in these types of businesses [00:39:07] - Is big enabling technology shifts what manifests in successful outcomes? [00:40:37] - The role of media and how it intersects with investing [00:44:29] - What he attributes to the success of his firm and thriving in chaos [00:48:11] - Would he press a button that would have made his childhood easy, and whether he’s met founders who haven’t come across adversity in their lives  [00:50:00] - His thoughts on the world today via the lens of his portfolio [00:53:12] - The kindest thing anyone has ever done for him

Jimmy "MrBeast" Donaldson is an internet personality, businessman, and philanthropist. He operates several popular YouTube channels, a delivery based fast food restaurant, MrBeast Burger, and two philanthropic programs: Beast Philanthropy, and Team Trees. Learn more about your ad choices. Visit podcastchoices.com/adchoices

From helping build smart cities to supporting the sustainable energy sector, the possibilities of big data are endless. But many companies are still wary of sharing data that could expose them to risk and diminish their competitive advantage. What if uniting towards a common goal could help them overcome these fears? Data cooperation expert Massimo Russo shares three ways to jump-start a virtuous cycle of data sharing -- and how it can lead to better climate change solutions.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Born in the unlikeliest of places — the terrible, wasteland-like aftermath of post WWII Japan — Sony rose to capture the imaginations (and wallets) of consumers and engineers around the world. The company produced hit after hit after hit: portable transistor radios, CDs, the Walkman, the PlayStation, DVDs, life insurance(!!)... and yet ultimately fell behind its greatest American admirer, Steve Jobs and Apple. This is the incredible story of Sony’s human and technological optimism in the face of overwhelming odds — a story that, given recent world events, remains as relevant today as ever.This episode has video! You can watch it on YouTube.Sponsors:WorkOS: https://bit.ly/workos25Sierra: https://bit.ly/acquiredsierraSentry: https://bit.ly/acquiredsentryAnthropic: https://bit.ly/acquiredclaude25More Acquired!Get email updates with hints on next episode and follow-ups from recent episodesJoin the SlackSubscribe to ACQ2Merch Store!© Copyright 2015-2025 ACQ, LLCLinks:Steve Jobs’ Tribute to Akio Morita: https://youtu.be/Drwkvf76ClsPlanet Money on Sony and Spider-Man: https://www.npr.org/2022/01/28/1076531156/the-spider-man-problemEpisode sources:  https://docs.google.com/document/d/1LpnPSju5xSPcuaRVd1TYXnL1oGBr4Qs5bRS7owbxoEc/edit?usp=sharingCarve Outs:How This All Happened by Morgan Housel: https://www.collaborativefund.com/blog/how-this-all-happened/The Model 3 is AWESOME: https://www.tesla.com/model3‍Note: Acquired hosts and guests may hold assets discussed in this episode. This podcast is not investment advice, and is intended for informational and entertainment purposes only. You should do your own research and make your own independent decisions when considering any financial transactions.