🇺🇸 United States Episodes

Show Notes: 00:00 Cold Open 01:19 Titles 01:01 Intro Banter 04:24 Supply chain, labor shortage,  34:04 Taiwan 43:14 Sacks Desantis 47:00 Dave Chappelle 01:08:24 FDA 01:23:27 Question 1 01:27:08 Question 2   Follow the besties:  https://twitter.com/chamath https://linktr.ee/calacanis https://twitter.com/DavidSacks https://twitter.com/friedberg   Follow the pod: https://twitter.com/theallinpod https://linktr.ee/allinpodcast   Intro Music Credit: https://rb.gy/tppkzl https://twitter.com/yung_spielburg   Intro Video Credit: https://twitter.com/TheZachEffect   Referenced in the show: Statista - The U.S. Car Models Most Impacted By The Microchip Shortage Zack Kanter on Twitter - "The "supply chain crisis" is a clever rebrand" Naithan Jones on Twitter - NFTs Daily Breeze - No start date for 24/7 operations at Port of LA LA Daily News - Port of LA to go to 24/7 operations, Biden announces Nikkei Asia - TSMC announces plans to build first chip plant in Japan St. Louis Fed - Total Public Debt as Percent of Gross Domestic Product Forbes - Druckenmiller Blasts Fed's 'Radical' Stimulus Policy David Sacks on Twitter - Desantis Dinner Variety - Ted Sarandos Doubles Down The Light of Other Days by Arthur C. Clarke CFTC Orders Tether and Bitfinex to Pay Fines Totaling $42.5 Million NBC -  Most adults shouldn't take daily aspirin Botched - Man Wins $100,000 Breast Implants Bet!

Today’s episode is all about crypto security — that is, the new mindsets and the new strategies for storing crypto assets safely while also allowing holders control and access. As a reminder, none of the following should be taken as investment advice, please see a16z.com/disclosures for more important information. We’ve covered security trends more broadly a ton in our content, which you can find at a16z.com/security, as well as crypto-related trends including NFTs, and the creator and ownership economies; you can find all of that at a16z.com/nfts But as more people enter crypto lately — thanks to the boom in NFTs, decentralized finance, and much more — we share specific best practices and options for securing crypto as well as discussing how it all fits this next evolution of the internet: web3. Our expert today is a16z crypto data scientist Eddy Lazzarin, who joins host Zoran Basich to cover practical approaches ranging from passwords to crypto wallets and what users can do; the evolution of crypto briefly; and the big picture mindset shifts involved here as well. We quickly begin with the practical shift crypto security represents compared to how people interact with traditional financial institutions, and then we go into the big picture trends in security when it comes to abstraction and usability. Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Tony Hinchcliffe is a stand-up comedian, writer, and actor. He's also the co-host, along with Brian Redban, of the podcast and live YouTube show Kill Tony. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Skin is one of the most powerful predictors of health, yet nearly half of all new dermatologists admit to feeling uncomfortable identifying health issues on darker skin tones -- resulting in poorer health outcomes for patients of color. In this crucial talk, TED Fellow and dermatologist Jenna C. Lester shares her effort to extend medical training beyond its current limited scope and ensure all medical students get trained in the full spectrum of diseases as they appear in all patients, regardless of skin tone.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

The power of slowing down during difficult workplace situations.

Kelsi Sheren is a veteran, artillery gunner, and founder of Brass and Unity. Please support this podcast by checking out our sponsors: – Shopify: https://shopify.com/lex to get 14-day free trial – Justworks: https://justworks.com – Novo: https://banknovo.com/lex – Indeed: https://indeed.com/lex to get $75 credit – Onnit: https://lexfridman.com/onnit to get up to 10% off EPISODE LINKS: Kelsi’s Twitter: https://twitter.com/kelsiburns Kelsi’s Website: https://brassandunity.com Kelsi’s Instagram: https://www.instagram.com/kelsie_sheren Charity: https://www.heroicheartsproject.org/ Do the F*cking Work (book): https://amzn.to/3mGhguF Notes from Underground (book): https://amzn.to/3mN5TRF Brothers in Arms (song): https://www.youtube.com/watch?v=jhdFe3evXpk PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/lexfridman – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:50) – World War II (18:54) – Yeonmi Park, starvation, and mental health (33:10) – Kelsi’s 9/11 experience (36:39) – Becoming a soldier (43:07) – Artillery: The Hand of God (52:49) – Weapons training (1:10:35) – Pre-Deployment (1:26:42) – Arrival to Afghanistan (1:48:55) – Tragic war story (2:13:59) – Feelings after tragedy (2:17:41) – The Taliban (2:23:17) – Retrospective: 20 years in Afghanistan (2:39:57) – How war changes people (2:45:18) – PTSD (3:14:13) – Ayahuasca and mental recovery (3:46:09) – Love (4:04:12) – Advice for young people (4:07:33) – Death (4:13:22) – World War II

Michael Shellenberger is a journalist and author. His latest book, "San Fransicko: Why Progressives Ruin Cities," will be published on October 12, 2021. Learn more about your ad choices. Visit podcastchoices.com/adchoices

The roadmap to ending pollution from transportation is here, says electrification advocate Monica Araya. In conversation with head of TED Chris Anderson, Araya introduces Drive Electric: a global campaign to retire the polluting internal combustion engine in time to avoid climate disaster. And she shares some exciting news: a breakthrough funding commitment from the Audacious Project that puts the project well on its way to realizing a billion-dollar plan to supercharge the transition to electric vehicles over the next five years. Learn more about the coalition of 70 organizations powering this global action -- and the role all cities, politicians and citizens can play to secure a zero-emission transport future. (This ambitious plan is a part of the Audacious Project, TED's initiative to inspire and fund global change.)Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Brian Halligan (@BHalligan), founder & executive chairman (and former CEO) of HubSpot, joins Sam (@TheSamParr) and Shaan (@ShaanVP) to discuss what he learned from nearly dying in a snowmobile accident, how he took HubSpot from nothing to $1 billion in ARR, and what he learned about marketing from the Grateful Dead. He also discusses what he does day-to-day, why he has always preferred inbound marketing, how to manage creatives, and much more. --------- * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel. * Want more insights like MFM? Check out Shaan's newsletter. --------- Show Notes: * (1:37) Brian’s snowmobiling accident that nearly killed him * (7:18) How Brian’s life has changed since * (13:07) What Brian actually does day-to-day * (28:39) Why has always Brian preferred inbound marketing * (32:00) Businesses that can be built on top of HubSpot * (33:34) Org chart business opportunities * (36:14) Climate Tech Opportunities * (50:50) How to Manage Creatives * (55:35) What the Grateful Dead can teach us about marketing

In the last year, Sarah Hirshland has had to face one daunting issue after another as the CEO of the U.S. Olympic & Paralympic Committee – each of which have required urgent, in-the-moment decisions. Most recently Sarah mandated that U.S. athletes be vaccinated against COVID-19 to participate in the upcoming Beijing winter games. But that’s just the latest of a slew of cultural issues she’s been tasked to act on. She’s faced pandemic disruptions, social action protests, sexual misconduct scandals, mental health stress, and more. Through all of it, Sarah has been motivating her team around an evolving mission to reflect not just where America is as a country today but where it’s going.  Read a transcript of this interview at: mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Zack Telander is a weightlifter, coach & YouTuber. ZT joins me to talk about the world's most pressing issues like whether men should be forced to get vasectomies at age 40, if Jon Jones can ever find redemption, why New Zealand's football team name is problematic, why the female orgasm is so elusive, how Zack got involved in internet beef with a big Texan man, whether CrossFit has rampant steroid use and much more... Sponsors: Get 20% discount on Reebok’s entire range including the amazing Nano X1 at https://geni.us/modernwisdom (use code MW20) Reclaim your fitness and book a Free Consultation Call with ActiveLifeRX at http://bit.ly/rxwisdom Extra Stuff: Subscribe to Zack's YouTube Channel -https://www.youtube.com/channel/UC94_fvLx7abZgs9LIkM7jxw  Get Zack's Program for $1 - https://www.patreon.com/zacktelander Follow Zack on Instagram - https://www.instagram.com/coach_zt Get my free Reading List of 100 books to read before you die → https://chriswillx.com/books/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me... Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/ModernWisdomPodcast Email: https://chriswillx.com/contact/  Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Sanjay Gupta is a practicing neurosurgeon, chief medical correspondent for CNN, and host of the network's podcast "Chasing Life." His new book, "World War C: Lessons from the Covid-19 Pandemic and How to Prepare for the Next One," is available now. Learn more about your ad choices. Visit podcastchoices.com/adchoices

From September 11, 1998 Oprah Winfrey Show: Iyanla Vanzant, author of "In The Meantime: Finding Yourself And The One You Want" and "One Day My Soul Just Opened Up," talks about how to love yourself and counsels women in the audience about how to change what you believe, in order to get what you want. Iyanla also talks about how she connects with her spirit.

Activism is a tough job, especially for young people yearning for immediate change -- something climate activist Melati Wijsen has learned over ten years of pushing for environmental protection, starting at age 12 in her home on the island of Bali, Indonesia. How can young changemakers acquire the skills they need and keep from burning out? Wijsen offers three pieces of advice for anybody seeking to make lasting, sustainable progress.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Sam Parr (@theSamParr) and Shaan Puri (@ShaanVP) discuss Brumate, the company that scaled to $20M without a single employee, how F*** You Pay Me is helping influencers discover what they’re truly worth, how to do an energy audit, and much more. --------- * Do you love MFM and want to see Sam and Shaan's smiling faces? Subscribe to our Youtube channel * Want more insights like MFM? Check out Shaan's newsletter --------- Show Notes: 0:00 - Recapping Rob Dyrdek and when to work to be most productive 10:35 - How to do an “energy audit” 12:50 - Brumate - the company making $20M with 0 employees 17:40 - Companies making businesses selling water bottles 19:45 - How MVMT sold for $100M+ 21:50 - Shaan will start a coconut water brand with you 26:47 - Carpet cleaner businesses - the perfect teenager side hustle 29:35 - The life-changing power of making your first side-hustle dollar 31:40 - Billy of the Week: Shahid Khan 40:55 - F*** You Pay Me - how influencers are getting paid 44:00 - How to make better investor updates 48:00 - Sam’s update on becoming a fitness influencer 54:25 - Why Shaan gets free merch and Sam doesn’t --------- Links: * vcguide.co * F*** You Pay Me * MVMT * Brumate * Cabal

Alex Berenson is a journalist and author of both fiction and non-fiction. His latest book, "Pandemia: How Coronavirus Hysteria Took Over Our Government, Rights, and Lives," will be published on November 30, 2021. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Technological development is happening faster than ever and changing our lives in fundamental ways. The companies behind all these new gadgets and services are no doubt the greatest corporate success stories of our age. But entrepreneur and investor Azeem Azhar worries that our public institutions haven't kept pace with the industry, which has created an exponential gap between digital haves and have nots. He offers recommendations on how bridge the divide and achieve growth with broader societal benefits. You can hear more from Azeem Azhar on his HBR Presents podcast, Exponential View.

Jessica Alba’s approach in founding and building The Honest Company revolves around three letters: IRL, a useful acronym for “In Real Life.” This phrase acts as a reminder for the company to shine the spotlight onto their customer’s real needs – not only to understand them, but to address them as well. Alba built the company around her passion to make childcare and household products that are safe and eco-friendly. By asking her team “What’s the IRL version of this?”, Alba focuses the company to make products that will enhance the customer’s everyday lives. “A lot of these product ideas come from: What do I wish I had to optimize the life experience – and then, how can we do it?” Read a transcript of this episode: https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

My guest today is Nick Neuman, CEO and co-founder of Casa. Casa helps bitcoin investors and owners keep their digital assets safe from loss or theft by providing managed self-custody services. In our discussion, we cover the history of asset custody from ancient temples to decentralized ledgers, look at the mechanics of how private keys work, and explore why people are better off holding the keys themselves. We then dive into the future of digital wallets as gateways into our virtual lives, what’s interesting about identity authentication more broadly, and whether these innovations may lead to unintended consequences. Please enjoy this great conversation with Nick Neuman.   For the full show notes, transcript, and links to the best content to learn more, check out the episode page here.   ------   Invest Like the Best is a property of Colossus, Inc. For more episodes of Invest Like the Best, visit joincolossus.com/episodes.    Past guests include Tobi Lutke, Kevin Systrom, Mike Krieger, John Collison, Kat Cole, Marc Andreessen, Matthew Ball, Bill Gurley, Anu Hariharan, Ben Thompson, and many more.   Stay up to date on all our podcasts by signing up to Colossus Weekly, our quick dive every Sunday highlighting the top business and investing concepts from our podcasts and the best of what we read that week. Sign up here.   Follow us on Twitter: @patrick_oshag | @JoinColossus   Show Notes [00:03:23] - [First question] - The history of asset custody [00:07:56] - What private keys are and their role in financial security  [00:12:21] - Overview of storing a token in a wallet and accessing with a private key  [00:15:28] - Thoughts on private keys through the lenses of convenience and safety [00:18:49] - Solving both self-custody of assets and peace of mind [00:21:39] - How the user experience will feel once self-custody is properly developed [00:24:11] - Why asset custody is so interesting and what a perfect scenario unlocks [00:27:05] - Is the DeFi ecosystem an early manifestation of a self-custody financial system  [00:28:57] - Ways Casa is planning to become a convenient and diverse platform for users [00:32:16] - The role wallets will play in the future of a digital world [00:34:56] - Forms of authentication that are most appealing in creating a seamless user experience [00:37:39] - Overview of what hardware wallets are and how they work [00:40:17] - Different security options that Casa offers from the simplest to the most secure [00:44:51] - How many crypto holders there are and how many use self-custody [00:47:31] - The craziest security set up around Bitcoin he’s ever heard of  [00:48:49] - What the most ideal outcome for Casa looks like in the coming decade  [00:51:26] - Thoughts on the competitive landscape and potential growth challenges  [00:53:07] - Important aspects of the crypto ecosystem other than security   [00:55:49] - How empowered people feel when they successfully adopt self-custody [00:57:13] - Whether or not there are ways that the current centralized system is more secure [00:59:58] - Thoughts on offering a way for users to display they are protected by Casa  [01:01:31] - The kindest thing anyone has ever done for him

This episode I discuss the science and practice of fasting also called time-restricted feeding. I review the data on how limiting food intake to specific portions of every 24-hour cycle (or fasting longer) impacts weight loss, fat loss specifically, liver health, mental focus, muscle, longevity and more. I explain how "fasted" is contextual, and relates to blood glucose levels and their downstream effects, and how the depth of fasting can be adjusted with behaviors such as different types of exercise, or with glucose disposal agents. I also discuss the optimal fasting protocol: and both the absolute (non-negotiable) and variable (contextual) features of a fasting/time-restricted-feeding protocol that will allow you to get the most benefits. I also discuss what does and does not break a fast, the effects of fasting on hormones like testosterone and cortisol and on fertility. I also review how different feeding windows of 8 or 10 or 4 hours differentially impact the effects of fasting, and why the classic 8 hour feeding window came to be but also might be ideal. I discuss mechanisms and offer tools to discern the optimal fasting duration and timing for you.  Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Introduction, Blood Glucose & Mortality, Mice Vs. Humans   00:06:18 Sponsors: AG1, LMNT & Waking Up 00:09:42 Neuroplasticity Protocols & Online Lecture   00:11:20 Feeding, Fasting, Performance   00:13:50 Calories-In, Calories-Out (CICO); Perfect Diets   00:19:48 Feeding-Induced Health Conditions   00:25:33 Time Restricted Eating: When We Eat Is Vital   00:29:45 The Eight Hour Feeding Window   00:31:26 Feeding Deep Into the Night Is Bad (In Humans)   00:36:33 Liver Health   00:39:45 Time Restricted Feeding Protocol: Rules   00:41:35 When to Start & Stop Eating   00:45:38 Gastric Clearance, Linking Fasting to Sleep   00:52:35 Effects of Specific Categories of Food   00:55:40 Precision In Fasting: Protocol Build   00:59:30 4-6 Hour Feeding Windows   01:03:08 Protein Consumption & Timing for Muscle   01:08:13 How to Shift Your Eating Window   01:13:20 Glucose Clearing, Exercise & Compounds   01:22:37 Blood Glucose: Monitoring, mTOR & Related Pathways   01:27:40 Gut Health: Fasting, Clock Genes and Microbiota   01:29:15 Non-Alcoholic Fatty Liver   01:32:00 Effects of Fasting on Hormones: Testosterone, Cortisol   01:38:40 Fertility   01:41:50 8-Hour Feeding Window: Weight Loss Without Calorie Counting   01:43:20 Eating Every-Other-Day   01:45:29 Adherence   01:47:15 Mental Focus & Clarity   01:49:12 Enhancing Weight Loss from Body Fat: Hepatic Lipase   01:53:15 What Breaks a Fast? Rules & Context   01:58:50 Artificial Sweeteners, Plant-Based Sweeteners   02:01:42 Glucose Clearing II, Cinnamon, Acidity, Salt   02:06:42 My Circadian Clock, Zero-App   02:08:20 Odd (But Common) Questions   02:09:23 Effects of Sauna & Dehydration on Blood Glucose   02:11:12 The Ideal Fasting Protocol   02:24:00 More Resources, Ways to Support Us, Supplements   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices