🇺🇸 United States Episodes

Matthew W. Johnson is a professor and psychedelics researcher at Johns Hopkins. Please support this podcast by checking out our sponsors: – Brave: https://brave.com/lex – Neuro: https://www.getneuro.com and use code LEX to get 15% off – Four Sigmatic: https://foursigmatic.com/lex and use code LexPod to get up to 60% off – Cash App: https://cash.app/ and use code LexPodcast to get $10 EPISODE LINKS: Matt’s Twitter: https://twitter.com/Drug_Researcher Matt’s Website: https://www.hopkinsmedicine.org/profiles/results/directory/profile/0800020/matthew-johnson Study Website: https://hopkinspsychedelic.org/ PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (06:31) – Introduction to psychedelics (22:33) – Psychedelics expand the mind (25:44) – The priors we bring to the psychedelic experience (29:40) – Elon Musk and first principles thinking (40:10) – DMT (51:32) – Joe Rogan and DMT (57:40) – The nature of drug addiction (1:11:29) – The economics of drug pricing (1:17:44) – Should we legalize all drugs? (1:29:46) – What is the most dangerous drug? (1:32:20) – Does drug prohibition work? (1:36:14) – Cocaine and sex (1:43:15) – Risky sexual decisions (1:54:12) – Psilocybin helping people quit smoking (2:00:30) – Young Jamie (2:22:38) – Participating in a study (2:29:57) – Psychedelics and the human mind (2:37:20) – The future of psychedelics (2:40:01) – Neuralink (2:49:33) – Consciousness (3:02:15) – Panpsychism (3:12:20) – Aliens and DMT (3:22:24) – Mortality (3:32:12) – Meaning of life

Special omnibus episode combining two previous episodes on the a16z Podcast network, discussing the relevance, considerations, and problems/ solutios of the Paycheck Protection Program (or PPP) from the Small Business Administration (and the role of government stimulus/ pandemic relief for the economy) and where tech comes in.

Paul Evans is an entrepreneur and author. Out of body experiences during operations are bizarre but at least semi-common, living an entire new life in an alternate reality for two years during a seven month coma is something else entirely. Expect to learn how childhood bullying can set the tone for your entire life, what it was like to live through the Arab Spring revolts in Egypt, the mind bending detail that Paul can remember his "other life" in and much more... Sponsors: Get 20% discount on the best coffee in Britain with Uncommon Coffee’s entire range at http://uncommoncoffee.co.uk/ (use code MW20) Get 83% discount & 3 months free from Surfshark VPN at https://surfshark.deals/MODERNWISDOM (use code MODERNWISDOM) Extra Stuff: Buy When I Woke Up - https://amzn.to/2KfDJPm Follow Paul on Instagram - https://www.instagram.com/pauljohnevs/  Get my free Ultimate Life Hacks List to 10x your daily productivity → https://chriswillx.com/lifehacks/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me... Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/ModernWisdomPodcast Email: https://www.chriswillx.com/contact  Learn more about your ad choices. Visit megaphone.fm/adchoices

Also: which professions have the happiest people?

Michael Littman is a computer scientist at Brown University. Please support this podcast by checking out our sponsors: – SimpliSafe: https://simplisafe.com/lex and use code LEX to get a free security camera – ExpressVPN: https://expressvpn.com/lexpod and use code LexPod to get 3 months free – MasterClass: https://masterclass.com/lex to get 2 for price of 1 – BetterHelp: https://betterhelp.com/lex to get 10% off EPISODE LINKS: Michael’s Twitter: https://twitter.com/mlittmancs Michael’s Website: https://www.littmania.com/ Michael’s YouTube: https://www.youtube.com/user/mlittman PODCAST INFO: Podcast website: https://lexfridman.com/podcast Apple Podcasts: https://apple.co/2lwqZIr Spotify: https://spoti.fi/2nEwCF8 RSS: https://lexfridman.com/feed/podcast/ YouTube Full Episodes: https://youtube.com/lexfridman YouTube Clips: https://youtube.com/lexclips SUPPORT & CONNECT: – Check out the sponsors above, it’s the best way to support this podcast – Support on Patreon: https://www.patreon.com/lexfridman – Twitter: https://twitter.com/lexfridman – Instagram: https://www.instagram.com/lexfridman – LinkedIn: https://www.linkedin.com/in/lexfridman – Facebook: https://www.facebook.com/LexFridmanPage – Medium: https://medium.com/@lexfridman OUTLINE: Here’s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. (00:00) – Introduction (07:43) – Robot and Frank (10:02) – Music (13:13) – Starring in a TurboTax commercial (23:26) – Existential risks of AI (41:48) – Reinforcement learning (1:07:36) – AlphaGo and David Silver (1:17:15) – Will neural networks achieve AGI? (1:29:42) – Bitter Lesson (1:42:32) – Does driving require a theory of mind? (1:51:58) – Book Recommendations (1:57:20) – Meaning of life

Harold McGee is an author and food expert. Our sense of smell sits at the front of our daily experience and yet our understanding of what smells are and how they're processed is almost non existent. Expect to learn why smell may be the oldest of our senses, how our brains combine what hits our nose to create sensations, whether smell will be the new frontier for the entertainment industry, what an opera singer smells like and much more... Sponsors: Get 25% discount on all mindful toiletries from Michael Hannah at https://www.michaelhannah.co.uk (use code MW25) Get 20% discount & free shipping on your Lawnmower 3.0 at https://www.manscaped.com/ (use code MODERNWISDOM) Extra Stuff: Buy Nose Dive - https://amzn.to/3qHCEAY Follow Harold on Twitter - https://twitter.com/Harold_McGee Get my free Ultimate Life Hacks List to 10x your daily productivity → https://chriswillx.com/lifehacks/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me... Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/ModernWisdomPodcast Email: https://www.chriswillx.com/contact  Learn more about your ad choices. Visit megaphone.fm/adchoices

As a police officer, Jeremy Brewer interacts with individuals experiencing trauma and loss on a daily basis. Giving us a peek into this little-discussed aspect of the job, Brewer shares thoughtful insights on why respecting people's space is sometimes more important than trying to fix an unfixable moment -- and explains how you can use this approach to support someone when they need you the most.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Terry W. Virts is a retired astronaut, International Space Station Commander, test pilot, and colonel in the United States Air Force. Virts spent over 213 days in space over the course of his career with NASA. His new book How to Astronaut: An Insider's Guide to Leaving Planet Earth is now available. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) are joined by Jack Smith (@_jacksmith). They discuss: - (0:59) Introduction to Jack Smith - (7:04) Jack introduces the world of collectible card investing - (14:40) What is Rally Rd - (23:29) How to make money lending against trading cards - (32:52) Collecting NBA moments? - (37:00) The opportunities in trading cards - (47:00) The massive size of eBay's collectible business - (49:00) Shaan hears from a sketchy entrepreneur and they discuss cards as ETF Thank you to our sponsor this episode, Flatfile! Spend less time on Excel and more time building your business by easily importing data using Flatfile. Check them out at flatfile.io/hustle. Have you joined our private FB group yet? It's a page where people share each others million dollar ideas or what they're already working on: https://www.facebook.com/groups/ourfirstmillion.  See acast.com/privacy for privacy and opt-out information.

Over 13 years after its founding, one of the defining startup companies of the past decade finally makes its public debut — and boy was it a big one. But for all the hype (and all the legitimately great things Airbnb has accomplished), this is a company that looks very different today than in the past. Even before COVID, Airbnb's once-exponential bookings growth had declined to linear levels while the company's costs continued to balloon at accelerating rates. What’s going on here? Are public investors smart to bet on a permanent shift in travel behavior coming out of the pandemic? Or is this a case of unrealistic expectations? As always, we dive in. Sponsors:WorkOS: https://bit.ly/workos25Sierra: https://bit.ly/acquiredsierraSentry: https://bit.ly/acquiredsentryAnthropic: https://bit.ly/acquiredclaude25More Acquired!Get email updates with hints on next episode and follow-ups from recent episodesJoin the SlackSubscribe to ACQ2Merch Store!© Copyright 2015-2025 ACQ, LLCPlaybook Themes from this episode are available on our website at https://www.acquired.fm/episodes/airbnbCarve Outs:David — San Francisco Ballet's Nutcracker: https://www.sfballet.org/productions/nutcracker-online/Ben — Star Wars Lofi HipHop:  https://open.spotify.com/playlist/5iu1sp3UBb1rjf8KNKETtJ?si=WxPdJcRpSnelHN9qh0xYSw

Fairness matters ... to both people and primates. Sharing priceless footage of capuchin monkeys responding to perceived injustice, primatologist Sarah Brosnan explores why humans and monkeys evolved to care about equality -- and emphasizes the connection between a healthy, cooperative society and everyone getting their fair share.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

My guest today is Michelle Zatlyn. Michelle is the co-founder and COO of Cloudflare, a now $25 billion dollar business which she helped take public last year. Cloudflare helps businesses make their websites faster and more secure, and over 25 million websites are running Cloudflare today. In our conversation, we discuss the catalyst for starting CloudFlare, explore the layers of the internet and the future of distributed storage and computing power, and discuss how and why Cloudflare operates its network across 200 cities globally. We close with the importance of finding and working with great co-founders and partners as you build a business. I hope you enjoy our conversation.   DocSend is a document sharing platform that enables companies to share business-critical documents with ease and get real-time actionable analytics. With DocSend’s security and control, startup founders, investors, business development executives, and financial professionals can drive business outcomes that have a lasting impact. Start for free at www.docsend.com.    This episode of Founder’s Field Guide is also brought to you by NetSuite. Netsuite allows founders to centralize their payment systems, ditch old spreadsheets and Quickbook tools, and finally gain visibility and control over their financials, HR, inventory, eCommerce - all in one place, instantly. Whether you are doing a million in revenue or hundreds of millions in revenue - see why over 22,000 companies are using NetSuite today. Schedule your free product tour at https://www.netsuite.com/invest.   For more episodes go to InvestorFieldGuide.com/podcast. Sign up for the book club and new email newsletter called “Inside the Episode” at InvestorFieldGuide.com/bookclub. Follow Patrick on Twitter at @patrick_oshag   Show Notes (2:52) – (First question) – Project Honeypot and how it started (3:39) – What question was Honeypot solving (4:59) – Working through the idea maze of Cloudflare (7:30) – The first iteration of Cloudflare (8:15) – An overview of the cybersecurity market and why more leaders need to pay attention (10:33) – First big break for the company (12:50) – Risks they help mitigate (16:42) – Cyber weapons that Cloudflare protects against (20:14) – Hardest part of the building process (24:06) – Effective marketing lessons (25:41) – The sharks vs mosquitoes concept (27:53) – How do decide where to focus next (31:34) – The Cloudflare workers program (36:33) – Their scale vs other cloud providers (42:21) – The finance side of Cloudflare and their relationship vs Wall Street             (42:40) – John Collison Podcast Episode (44:47) – Relationship with their founding partners (50:46) – What about the future is most excites them (52:32) – Kindest thing anyone has done for her   Learn More For more episodes go to InvestorFieldGuide.com/podcast. Sign up for the book club and new email newsletter called “Inside the Episode” at InvestorFieldGuide.com/bookclub. Follow Patrick on Twitter at @patrick_oshag

Why leave a storied tech icon to lead a troubled brand? As the pandemic deepened this summer, Peggy Johnson left a safe perch at Microsoft to take the helm of one-time startup darling Magic Leap, which had just barely avoided bankruptcy. Yet with CEO roles for women in tech still unfortunately rare, Johnson felt compelled to take a risk. Now she's betting that the accelerated tech adoption prompted by Covid-19 will boost emerging areas like Magic Leap's AR. All entrepreneurs face moments when the bar seems impossibly high. But even in difficult times, Johnson knows, we can make our own opportunities.Read a transcript of this episode at https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter at https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Nims Purja MBE is a mountaineer and former SBS Operative. The fastest anyone had previously climbed the 14 Death Zone mountains greater than 8000m was 8 years. Nims Purja did it in 7 months. Expect to learn what the human body is truly capable of, how purpose can overcome fatigue, the truth behind "that Everest photo", what effect Nims has noticed climate change has made to the mountains and much more... Sponsors: Get 10% discount on everything from Slaters Menswear at https://www.slaters.co.uk/modernwisdom (use code MW10) Get 35% discount on everything I use from The Protein Works at https://www.theproteinworks.com/modernwisdom/ (use code MODERN35) Extra Stuff: Buy Beyond Possible - https://amzn.to/3fV5kkJ  Follow Nims on Instagram - https://www.instagram.com/nimsdai/  Get my free Ultimate Life Hacks List to 10x your daily productivity → https://chriswillx.com/lifehacks/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me... Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/ModernWisdomPodcast Email: https://www.chriswillx.com/contact  Learn more about your ad choices. Visit megaphone.fm/adchoices

Live from the scene of its blockbuster IPO, we recount the crazy, roller coaster journey of this "Palo Alto delivery company". From Sand Hill darling during their Series A and B fundraises to all but left-for-dead during the great unicorn massacre of 2015/16, DoorDash has clawed their way back from the brink and emerged as America's dominant meal delivery service, and its only unit-economic positive standalone logistics player. Is this the dawn of the next great Amazon-like story, or is the company simply benefiting from temporary tailwinds due to the pandemic? As always, we dive DEEP to find out. Sponsors:WorkOS: https://bit.ly/workos25Sierra: https://bit.ly/acquiredsierraSentry: https://bit.ly/acquiredsentryAnthropic: https://bit.ly/acquiredclaude25More Acquired!Get email updates with hints on next episode and follow-ups from recent episodesJoin the SlackSubscribe to ACQ2Merch Store!© Copyright 2015-2025 ACQ, LLCPlaybook Themes from this episode are available on our website at https://www.acquired.fm/episodes/doordashCarve Outs:David:Hades on the Nintendo Switch: https://www.nintendo.com/games/detail/hades-switch/Ben:Watchmen on HBO: https://www.hbo.com/watchmenSuccession on HBO: https://www.hbo.com/successionPalm Springs: https://www.imdb.com/title/tt9484998/

Have you ever seen or experienced something and wished you spoke up? Writer Sakinah Hofler makes the case for writing as a tool to help you process difficult memories and reclaim the power they may hold over you. Pick up a pen or pull up a keyboard and follow along as she walks you through how to unburden your mind and inspire reflection.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Shaan Puri (@ShaanVP) and Sam Parr (@TheSamParr) are joined by Superhuman's Rahul Vohra (@rahulvohra). They discuss: - Rahul's first startup, Rapportive - Rahul explain what it's like to work with Marc Andreesen - Will Superhuman go public? - Why doesn't Google crush Superhuman? - Rahul describes when the idea to create Superhuman struck him - Shaan asks, what're the best "Superhuman for X" ideas - How Rahul stays calm and manages time - What startups are Rahul investing in? - Rahul's startup ideas Thank you to our sponsor this episode, EPOS! EPOS are fantastic headsets that make it easy to work flexibly across situations and locations, with portable headsets including hassle-free device compatibility. If you are an IT manager running a big department or a head of a growing company looking to give your employees the best headset solution to work from home, check out eposaudio.com/millions for a free trial! Have you joined our private FB group yet? It's a page where people share each others million dollar ideas or what they're already working on: https://www.facebook.com/groups/ourfirstmillion.  See acast.com/privacy for privacy and opt-out information.

Oprah Winfrey talks with some of today’s most admired thought leaders, writers and thinkers, gathering some of the most powerful spiritual lessons on the subject of “awakening.” Based on her New York Times best-selling book, The Wisdom of Sundays, this episode is a compilation of some of Oprah’s most profound conversations with guests from her Emmy Award-winning show SuperSoul Sunday. World-renowned visionaries—including Caroline Myss, Gary Zukav, Eckhart Tolle, Sue Monk Kidd, Deepak Chopra, Jack Kornfield, Elizabeth Lesser, Rob Bell, Llewellyn Vaughn Lee, Sister Joan Chittister, Thomas Moore, Elizabeth Gilbert and Michael Singer—share their soulful wisdom and life-changing experiences on what it means to live an awakened life. They also prompt each of us to ponder those burning essential questions: Who am I? Where did I come from? Where am I going? What am I here for?

Mariana van Zeller is an award-winning journalist and documentarian. Her latest project is Trafficked: a National Geographic television series that takes her deep into the most dangerous black markets in the world. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In the Yukon First Nations, women lead; generations of matriarchs have guided and directed the community by forging trade agreements, creating marriage alliances and ensuring business for all. Yukon Regional Chief Kluane Adamek urges others to follow in the legacy of her people by putting more women at the table and encouraging them to seek spaces where their perspectives can create the biggest impact for a better tomorrow.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.