🇺🇸 United States Episodes

with @rvenkayya @jorgecondebio WHEN are we going to have a COVID-19 vaccine, and how the heck are we going from 12 years of vaccine development compressed into 12 months or so? What will and won’t be compromised here, and where do new technologies (like mRNA) come in? Where will vaccines likely be distributed first; who will and won't get them initially; how do we maintain not just safety and efficacy of vaccines but trust and transparency when it comes to mis/information? We may actually see the emergence of a "Neo Anti-Vaxxer"... but we may also be entering a renaissance for vaccinology after this pandemic.

Sam Parr (@theSamParr) and Shaan Puri (@ShaanVP) bring back Ryan Begelman (@ryanbegelman) for round two on the podcast. In today’s episode you’ll hear: Ryan explains his idea on how high-end cooking classes could make you a million dollars a year (3:00), Ryan talks about some of the very first big name celebrities to join Summit Series (8:15), Shaan asks Ryan if Adam Neumann from WeWork took entity structure too far (11:20), Ryan gives his thesis on how you structure a business following “The Virgin Model” (14:10), Shaan asks Ryan to expand on how to create wealth while still having a great life (25:10), Ryan pulls the curtain back on what it’s like to work in big banking and private equity (33:00), Shaan explains his “sell your byproduct” framework (45:12), Ryan outlines how to grow your business without venture capital (48:05), the guys talk about the psychology behind selling a high-ticket item (52:35) Companies and people mentioned: - Ryan Begelman’s website: https://www.ryanbegelman.com/ - Ryan’s companies: https://summit.co/ and https://www.bisnow.com/ - https://websummit.com/ was founded by Paddy Cosgrave (https://en.wikipedia.org/wiki/Paddy_Cosgrave) - Adam Nuemann, WeWork founder: https://en.wikipedia.org/wiki/Adam_Neumann - https://harvesthosts.com/ founded by Joe Holland - Barry Sternlicht (https://en.wikipedia.org/wiki/Barry_Sternlicht) founder of Starwood Capital, and https://en.wikipedia.org/wiki/Baccarat_(company), the company bought. This episode is presented by Tempo! Check them out at tempo.fit and use code "TempoHustle" for $100 off. Joined our private FB group yet? It's a page where people share each others million dollar ideas or what they're already working on: https://www.facebook.com/groups/ourfirstmillion.  See acast.com/privacy for privacy and opt-out information.

Tim Dillon is a comedian, tour guide, and host. His podcast “The Tim Dillon Show” is available on Spotify. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Consider the following scenario: a highly infectious, sometimes deadly respiratory virus infects humans for the first time. It spreads rapidly worldwide, and the WHO declares a pandemic. The death toll starts to rise and everyone is asking the same question: when will the pandemic end? Alex Rosenthal details the three main strategies governments can use to contain and end a pandemic. [Directed by Visorama, narrated by Jack Cutmore-Scott, music by Bamm Bamm Wolfgang].Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Audience questions that range from how to handle interrupters to how to craft an authentic, clear email.

Jonny & Yusef join me again to discuss our experience as humans over the last few months. No agenda, just finding out what's been going on in life. I've lost an achilles, Bill Ackman made the greatest trade in history, Netflix has some amazing content on, Jonny's dog joins us and we discuss cinnamon a lot. Sponsor: Get Surfshark VPN at https://surfshark.deals/MODERNWISDOM (Enter promo code MODERNWISDOM for 85% off and 3 Months Free) Extra Stuff: Free business training to become an online coach - https://propanefitness.com/modernwisdom Gain muscle & lose fat - https://propanefitness.com/ Get my free Ultimate Life Hacks List to 10x your daily productivity → https://chriswillx.com/lifehacks/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me... Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/ModernWisdomPodcast Email: https://www.chriswillx.com/contact Learn more about your ad choices. Visit megaphone.fm/adchoices

Ron Funches is a comedian, actor and writer. His podcast "Gettin' Better" is available on Spotify. On September 5, his live stand up event "Awakening" will be streaming on YouTube and tickets are now available here: eventbrite.com/e/ron-funches-awakening-tickets-113410704470 Learn more about your ad choices. Visit podcastchoices.com/adchoices

What can you hear in silence? In this exploration of sound, host of the podcast "Twenty Thousand Hertz" Dallas Taylor tells the story of arguably the most debated musical composition in recent history -- composer John Cage's iconic piece 4'33" -- and invites you to take notice of the soundscape around you. Watch to the end to experience a performance of 4'33''.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Sam Parr (@theSamParr) and Shaan Puri (@ShaanVP) are joined by Anthony Pompliano (@APompliano) to hear about his time at Facebook and kick around a few ideas. In today’s episode Pomp talks about his experience at Facebook and Snapchat (4:05), Pomp gives the background on how he got into tech after a career in the Army (11:25), Sam expounds on the book Tribes and the impact he thinks it can have on businesses looking to build camaraderie (18:50), Pomp pitches how to reinvent dating apps to be more authentic (24:25), all three of the guys talk about how to get customers to "hook" to your product (33:05), Shaan talks about the future of automation (41:05), the group talks about how good training programs can be huge recruitment tools (50:00). - https://twitter.com/APompliano: Anthony "Pomp" Pompliano - Investments Pomp’s made: https://www.imperfectfoods.com/ (Pomp invested at $12m valuation), https://www.everlywell.com/ (Pomp invested at a $15m valuation), https://cubcoats.com/ - Book recommendation: https://www.amazon.com/Tribe-Homecoming-Belonging-Sebastian-Junger/dp/1455566381 - https://lunchclub.ai/: Helps you make professional connections - https://thehustle.co/04212020-silicon-valley-clubhouse/: Audio-only social network - https://muzmatch.com/en-US/: Dating app for muslims - https://dilmil.co/: Indian dating app - https://launchdarkly.com/: Another example of an “export business”. LaunchDarkly is a “feature management” tool whose origin was within Facebook. - https://amplitude.com/: Helps companies boost engagement by analyzing data to show what signals to look for. - https://twitter.com/sweatystartup: Storage investor and service business advocate. - https://www.healthstream.com/: Teaches medical personnel latest procedures. An example of a - https://www.eagletransfer.com/: Commercial moving business owned by Sam’s father-in-law. - https://pos.toasttab.com/: POS restaurant system - https://bit.ly/2XR7sSY Convo between Kevin Systrom and Matt Cohler, on selling Instagram to Facebook This episode is presented by Tempo! Check them out at tempo.fit and use code "TempoHustle" for $100 off. Joined our private FB group yet? It's a page where people share each others million dollar ideas or what they're already working on: https://www.facebook.com/groups/ourfirstmillion.  See acast.com/privacy for privacy and opt-out information.

In 2013 Oprah, headed to the South of France for an intimate conversation with rock-and-roll legend Tina Turner. In the only television interview following the iconic singer's private wedding ceremony in Switzerland to longtime love Erwin Bach, Oprah joins Tina during a stop on their honeymoon to talk love, retirement and her private life out of the spotlight.

Joey “CoCo” Diaz is a Cuban-American stand up comedian and actor. Joey also hosts his own podcast called “The Church of What’s Happening Now", available on Spotify. Brian Redban is a comedian and the founder of the Deathsquad podcast network. Also look for him on “Kill Tony". Learn more about your ad choices. Visit podcastchoices.com/adchoices

At age 16, journalist and filmmaker Jose Antonio Vargas found out he was in the United States illegally. Since then, he’s been thinking deeply about immigration and what it means to be a US citizen -- whether it’s by birth, law or otherwise. In this powerful talk, Vargas calls for a shift in how we think about citizenship and encourages us all to reconsider our personal histories by answering three questions: Where did you come from? How did you get here? Who paid?Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

Jonah Berger, professor at the Wharton School of the University of Pennsylvania, says that most of us aren’t approaching persuasion the right way. Pushing people to behave how you’d like them to or believe the same things you do just doesn’t work, no matter how much data you give or how many emotional appeals you make. Studying both psychology and business, he’s found better tactics for bringing people over to your side. One of the keys? Asking questions so people feel like they’re making the decision to change. Berger is the author of the book "The Catalyst: How to Change Anyone's Mind."

Tinder. Top Gun. Roots. The Simpsons. What do they have in common? Media icon Barry Diller. We're re-airing a classic episode with some wise words. Barry is what we call an "infinite learner." He’s only interested in things he's never done before. And if they’ve never been done by ANYONE? Better yet. He succeeds by embracing that he is, in fact, a master of nothing. Entrepreneurs, take note: You just might be an infinite learner yourself, and Barry shares a lesson or two you can use.Listen to Part 2 of this interview, "Learn to unlearn": https://mastersofscale.com/learn-to-unlearn/Read a transcript of this episode at https://mastersofscale.comSubscribe to the Masters of Scale weekly newsletter at https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

My guest this week is Brian Armstrong, the co-founder and CEO of Coinbase. The topic of our conversation is the future of cryptocurrency and decentralized finance. Its been a while since I checked in on the world of crypto and while prices are still below the 2017 highs, there’s been a ton of additional work and infrastructure laid. We discuss the major events of the past decade and what might happen in the 2020s. Perhaps most interesting, we cover the potential benefits of a modernized financial system, which Coinbase hopes to help usher in. As I’m trying to do more in conversation with CEOs, we also discuss the lessons he’s learned building a business. Please enjoy my conversation with Brian Armstrong.   This week’s episode is sponsored by Bottomless. Bottomless is a smart coffee subscription which automatically re-orders coffee for you based on your consumption habits.    Bottomless is offering one month and your second bag of coffee for free at bottomless.com/patrick.   For more episodes go to InvestorFieldGuide.com/podcast. Sign up for the book club and new email newsletter called “Inside the Episode” at InvestorFieldGuide.com/bookclub. Follow Patrick on Twitter at @patrick_oshag   Show Notes (2:23) – (First question) – Most important developments in cryptocurrencies             (3:00) - What happened in crypto over the last decade (3:01) – What will happen to cryptocurrency in the 2020s (4:01) – Long term vision for Coinbase (6:57) – Why should we be aiming towards an open financial system (11:41) – How crypto improves the movement of money (14:22) – Creating sound money and currencies (16:21) – Why economic freedom is an important variable in what he’s trying to do (19:44)  - How economic freedom can happen with various regulators around the world and in different countries (22:49) – How Coinbase attracted its first users (26:33) – The December 2017 madness of cryptocurrencies (29:50) – How he thinks about recruiting teams and motivating them to be productive (33:40) – Mistakes with people he’s learned from (34:56) – Steering a product roadmap and creating a successful business (37:17) – What do the non-Bitcoin currencies offer that Bitcoin doesn’t (41:19) – Innovation in cryptocurrency that excites him: DeFi (43:40) – Interesting geographic locations and their impact on crypto (45:29) – How his thoughts on company building has changed over the years (46:47) – Battling any loss of confidence as a founder (51:01) – Improving decision making as a leader (53:54) – Aspects of the job that he loves the most today (56:25) – Largest impediments to mass adoption of crypto (58:25) – His curiosity for scientific research and bioengineering (59:19) – Advice that helped him that he would offer others (1:01:38) – Kindest thing anyone has done for him   Learn More For more episodes go to InvestorFieldGuide.com/podcast. Sign up for the book club and new email newsletter called “Inside the Episode” at InvestorFieldGuide.com/bookclub. Follow Patrick on Twitter at @patrick_oshag

We have archives of films, newspapers, even seeds -- what if we could make one for the entire surface of the earth? Drawing on his experience mapping an ancient city in the Honduran jungle, archaeologist Chris Fisher makes the case for scanning the whole planet with LiDAR -- a technology that uses lasers shot from an airplane to map the ground -- in order to preserve our cultural and ecological heritage.Learn more about our flagship conference happening this April at attend.ted.com/podcast Hosted on Acast. See acast.com/privacy for more information.

In this episode, we continue our community series with a recent discussion that applies to many kinds of community building. Today’s topic: How do you create a platform that people not only use, but tell their friends about? One that goes beyond just being useful and actually connects deeply with the user? In this discussion, which was recorded at our Crypto Startup School in April 2020, a16z General Partner Chris Dixon talked about building communities — specifically, communities of open-source developers — with GitHub cofounder Tom Preston-Werner. They discussed how to engage early users, how to turn them into your biggest advocates, how to create superfans, and more. Today, GitHub is the leading community for open-source developers and others. They also discuss in-person communities vs. distributed communities, a topic that is very top of mind today. Stay Updated: Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

A destined drop-in from writer, creator, and comedian-extraordinaire, Seth Rogen (An American Pickle, Pineapple Express, Knocked Up). The guys grill Seth on his newly brined movie, his early stand-up days, longstanding collaborations with Apatow and Goldberg... amongst a big bundle of other scintillations. Seth's new film "An American Pickle" is available on HBO Max.

Jamie Alderton is a coach, fitness model and author. Jamie has been to the peak of fitness modelling, multiple magazine front covers, stepping on stage at WBFF Worlds and a physique most men dream to have. Expect to learn what goals you chase once you've completed being lean. whether dieting to 4% bodyfat is it worth it, Jamie's favourite mindset strategies, how he's adapted his lifestyle to becoming a dad and much more... Sponsor: Shop Eleiko’s full range at https://www.shop.eleiko.com (enter code MW15 for 15% off everything) Extra Stuff: Follow Jamie on Instagram - https://www.instagram.com/jayalderton Check out Jamie's Website - https://www.jayalderton.com/ Get my free Ultimate Life Hacks List to 10x your daily productivity → https://chriswillx.com/lifehacks/ To support me on Patreon (thank you): https://www.patreon.com/modernwisdom - Get in touch. Join the discussion with me and other like minded listeners in the episode comments on the MW YouTube Channel or message me... Instagram: https://www.instagram.com/chriswillx Twitter: https://www.twitter.com/chriswillx YouTube: https://www.youtube.com/ModernWisdomPodcast Email: https://www.chriswillx.com/contact Learn more about your ad choices. Visit megaphone.fm/adchoices

with @jorgecondebio @andy23tran and @lr_bio On this episode of the a16z Journal Club we discuss new research using engineered T cells to attack and destroy the "sleeping" cells that build up as we age and underlie many age-related conditions. This research lays the groundwork for a possible therapy that, in addition to treating specific diseases like liver fibrosis, is broadly health-promoting and restorative as we age.